• S-Adenosylhomocysteine: Master Regulator of the Methylati...

  2025-10-01

  Explore the pivotal role of S-Adenosylhomocysteine (SAH) as a metabolic intermediate and methylation cycle regulator. This in-depth article reveals unique mechanisms, research applications, and advanced insights into SAH’s impact on homocysteine metabolism and methyltransferase inhibition.

• Plerixafor (AMD3100): Advanced Insights into CXCR4 Antago...

  2025-09-30

  Explore the multifaceted mechanisms and advanced research applications of Plerixafor (AMD3100), a leading CXCR4 chemokine receptor antagonist. This in-depth article offers a unique, forward-looking analysis of SDF-1/CXCR4 axis inhibition in cancer and stem cell biology.

• Sulfo-Cy3 Azide: Precision Fluorescent Labeling for Devel...

  2025-09-29

  Explore how Sulfo-Cy3 azide, a sulfonated hydrophilic fluorescent dye, empowers precise Click Chemistry fluorescent labeling in neurodevelopmental studies. This article uniquely integrates advanced bioconjugation strategies with emerging applications in mapping neuronal development.

• Aprotinin: Advanced Mechanisms in Fibrinolysis and Redox ...

  2025-09-28

  Explore how aprotinin, a potent bovine pancreatic trypsin inhibitor, uniquely modulates serine protease signaling and redox balance for superior surgical bleeding control and cardiovascular research. This article provides a novel systems-biology perspective distinct from standard biochemical or membrane-centric reviews.

• Sulfo-NHS-SS-Biotin: Precision Mapping of Cell Surface Pr...

  2025-09-27

  Unlock the full power of Sulfo-NHS-SS-Biotin, a leading amine-reactive biotinylation reagent, for advanced cell surface protein labeling and dynamic proteome analysis. Discover unique mechanistic insights, workflow innovations, and targeted strategies for affinity purification that elevate your biochemical research.

• NHS-Biotin: Enabling Precision Biotinylation for Next-Gen...

  2025-09-26

  Discover how NHS-Biotin, a leading amine-reactive biotinylation reagent, empowers advanced intracellular protein labeling and multimeric protein assembly. This article uniquely explores NHS-Biotin's pivotal role in emerging protein engineering strategies, including peptidisc-assisted clustering.

• Torin 1: Unveiling mTOR Inhibition in ER-Driven Lipid Hom...

  2025-09-25

  Explore how Torin 1, a potent mTOR inhibitor, enables a new era of mTOR signaling pathway research by connecting cell proliferation inhibition with ER lipid homeostasis. This article uniquely integrates advanced mechanistic insights with translational perspectives for cancer and metabolic disease research.

• Cell Counting Kit-8 (CCK-8): Redefining Sensitive Cell Vi...

  2025-09-24

  Explore how the Cell Counting Kit-8 (CCK-8) revolutionizes water-soluble tetrazolium salt-based cell viability assays with unmatched sensitivity and convenience. This article uniquely examines CCK-8’s molecular mechanisms and its transformative impact on complex biomedical research, from cancer to stem cell aging.

• Murine RNase Inhibitor: Safeguarding Circular RNA Vaccine...

  2025-09-23

  Explore the indispensable role of Murine RNase Inhibitor in preserving RNA integrity during the development of circular RNA vaccines and advanced RNA-based assays. Learn how this oxidation-resistant, mouse RNase inhibitor recombinant protein supports reliable results in molecular biology research.

• br Acetaldehyde One of the most

  2025-03-03

  

  Acetaldehyde One of the most common environmental aldehydes is acetaldehyde (CH2CHO). Acetaldehyde, which is highly volatile, has been classified as a Group I human carcinogen by the International Agency for Research on Cancer [30]. Aldehydes can form DNA adducts, including ring-open forms of cro

• br Expression of adiponectin mRNA in chickens We first sough

  2025-03-03

  

  Expression of adiponectin mRNA in chickens We first sought to determine the nucleotide sequence of the chicken adiponectin cDNA. The open reading frame of the chicken adiponectin cDNA consists of 735 nucleotides that was 65–68% homologous to various mammalian adiponectin cDNAs (Maddineni et al.,

• Mast cells Mast cells are immune

  2025-03-03

  

  Mast cells. Mast Free radical scavenger are immune cells of the myeloid lineage and are ubiquitously present in connective tissues [75]. These cells are involved in the modulation of a number of physiological functions, such as vasodilation, angiogenesis, bacterial, and parasite elimination [75]. M

• This study does have several limitations mainly

  2025-03-03

  

  This study does have several limitations, mainly related to the DMSO vehicle. While DMSO is a known anti-inflammatory mediator,5, 12 it has been shown to upregulate ALOX5, which was not seen in this study (as we are likely underpowered to detect this difference). A manifestation of this anti-inflamm

• br Dihydrotestosterone in adult fish and

  2025-03-03

  

  Dihydrotestosterone in adult fish and frogs New perspectives and next directions Similar to other androgens, DHT can modulate reproductive endpoints in both fish and amphibians. However, predicting the effects of DHT can be challenging, as reproductive homeostasis is dependent upon the balance

• AXL is a member of the

  2025-03-03

  

  AXL is a member of the TAM (Tyro3, Axl, Mer) family of receptor tyrosine kinases (RTKs) [4]. Elevated AXL expression could promote oncogenic processes such as cell growth, migration, invasion, and epithelial-to-mesenchymal transition (EMT), which substantially contribute to tumor progression and poo

16125 records 8/1075 page Previous Next First page 上5页 678910 下5页 Last page