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br Discussion The natural history of PMF is
2019-05-21

Discussion The natural history of PMF is characterized by the possibility of blastic transformation in approximately 20% of all the cases [9]. Several factors might predict leukemic transformation, including percentage of circulating blasts, low platelets count and the presence of an unfavorable
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The outcome of sinus node
2019-05-20

The outcome of sinus node modification with radiofrequency ablation has been reported, but it involves a high invasive risk associated with the ablation. Thus, careful confirmation of the earliest activation site and ablation of that site is important [2,3]. The clinical use of the 3D-mapping system
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The two statements from the BRICS partnership could help to
2019-05-20

The two statements from the BRICS partnership could help to inform how best emerging economies can contribute to achievement of ambitious global targets for tuberculosis control. BRICS and other economies in transition have a great responsibility and the potential to contribute to all aspects of car
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buy Pitolisant hydrochloride The need for better measurement
2019-05-20

The need for better measurement of gender empowerment cannot be understated, given that 80% of indicators to monitor SDG5 lack adequate data, often because of an absence of valid measures. Although measures of gender empowerment are available, and more are being developed, there is no consensus on t
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En cualquier caso sabemos que esta pol
2019-05-20

En cualquier caso, sabemos que esta política admonitoria del Corpus obtuvo resultados abundantes que refrendaron la inserción beneficiosa de altas dosis de tremendismo en una catequesis ya no necesariamente diáfana. Incluso contamos con las huellas de una recepción defectuosa del sacramento que llev
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En correspondencia con ese posicionamiento cr
2019-05-20

En correspondencia con ese posicionamiento crítico frente p2y inhibitor la propuesta de cambio social de sus respectivos gobiernos, los movimientos sociales tienen entre sus principales objetivos la autonomía material y simbólica, considerada una de las características comunes en el contexto de la a
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He querido citar este pasaje del art culo de
2019-05-20

He querido citar este pasaje del artículo de Eudocio Becerra para mostrar cómo, sin quererlo, esta manera occidental de abordar la cuestión del estatuto ontológico y epistemológico que la palabra tiene para los uitotos, conduce al mismo callejón sin salida en el que desembocaron los estudios que él
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br Conformational control inhibition Conformational escape r
2019-05-20

Conformational control inhibition Conformational escape resistance is a phenomenon where point mutations (such as T315I) drive the Abl kinase toward the active type I state. “Switch-control inhibitors” bind in a non-ATP-competitive fashion to residues (E282, R386) the Abl protein uses to switch b
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br Introduction Acute myeloid leukemia AML remains a
2019-05-20

Introduction Acute myeloid leukemia (AML) remains a hematologic malignancy with poor outcome and a high risk for relapse believed to be caused by the survival of leukemic stem cells (LSCs), which are responsible for disease repopulation following treatment [1]. This important implication of LSCs
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In the past two decades several
2019-05-20

In the past two decades, several studies have consistently found that up to one-sixth of cancers worldwide are attributable to infectious pathogens. Cancers caused by infectious agents present unique opportunities for prevention and treatment; therefore, a detailed understanding of how infections co
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Two fundamental objections to the conclusion that mass dewor
2019-05-20

Two fundamental objections to the conclusion that mass deworming for helminths has no benefits and could therefore be abandoned have been repeatedly raised. First, the underlying studies might have been insufficient to detect benefits, because the follow-up for most studies was too short to detect h
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First Speakman and colleagues do
2019-05-20

First, Speakman and colleagues do not mention the developments in the 2000s, when notable EU attention was given to global health. In 2010, there was a high-level conference and the launch of a European Commission Communication, which stated that the EU\'s commitment to global health should mainly f
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Con esto no se pretende se alar que en el
2019-05-20

Con esto no se pretende señalar que en el terreno educativo no existan mentes lúcidas o que sus actores se comporten con una meridiana ingenuidad. Solamente queremos advertir que la constante necesidad de mejorar la educación y de aggiornar sus procesos glucose transport proteins la dinámica cambian
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br Materials and methods br Results br Discussion Although E
2019-05-20

Materials and methods Results Discussion Although EMT can be induced by different factors under exogenous stimuli, it is intriguing to consider whether these EMT inducers are redundant because of their mechanistic similarity in EMT induction. The interplay and underlying mechanism between E
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Immediate rollout of an effective and safe short course
2019-05-18

Immediate rollout of an effective and safe short-course treatment regimen is essential for the attack phase of the visceral leishmaniasis elimination programme, which aims to reduce the incidence to less than one case per 10 000 roscovitine at risk. A single-dose liposomal amphotericin B regimen, w
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