• It is noteworthy that even with

  2019-05-31

  

  It is noteworthy that, even with low tumor burden in these patients following CR, peak value at CR status is still a useful indicator for OS, both in the whole cohort, and more importantly, in the intermediate-risk subgroup. Slope is mainly determined by tissue vascularization and perfusion, but cap

• Programmed death ligand PD L expression is a characteristic

  2019-05-31

  

  Programmed death ligand 1 (PD-L1) expression is a characteristic feature of EBV-associated malignancies. Research has shown that an increase of PD-1-expressing intratumoral CD8 T cells predicts a poor prognosis for nasopharyngeal carcinoma. Preliminary data from a phase Ib study, KEYNOTE-028, showed

• br Conclusion br Acknowledgments br Introduction The bone is

  2019-05-31

  

  Conclusion Acknowledgments Introduction The bone is the most common site of tumor metastasis, in about 20–25% of cancer patients [1]. Bone metastases are most common from carcinomas of the breast, lung, prostate, kidney, and thyroid. Some bone metastases are osteoclastic, whereas others ar

• The lead ECG and dimensional

  2019-05-31

  

  The 12-lead ECG and 2-dimensional geometrical maps for corrected RT interval difference and corrected Tp–e interval difference obtained by using 187-ch RIDM-ECG before and during the intravenous amiodarone infusion for representative cases are shown in Figs. 1 and 2 respectively. The mean value of Q

• br Conclusions br Source of funding br Conflict of interest

  2019-05-31

  

  Conclusions Source of funding Conflict of interest Acknowledgments Introduction Atrial fibrillation (AF) is an arrhythmia that is commonly seen and occurs more often in the elderly. In Japan, the overall prevalence of all types of AF based on the data from periodic health examinations

• Nilotinib An enhanced T wave suppression mode was very effec

  2019-05-31

  

  An enhanced T wave suppression mode was very effective to manage TWOS and was able to detect induced and spontaneous VF correctly. On the other hand, it has been reported that Biotronik devices connected to integrated bipolar ICD leads from other manufacturers had an increased risk for oversensing [

• br Conclusiones br LA REVISTA DE FILOSOF A Para

  2019-05-30

  

  Conclusiones LA REVISTA DE FILOSOFÍA Para la época en que se publicaba la Revista de Filosofía, Cultura, Ciencias y Educación, José Ingenieros lideraba una agrupación nucleada en torno membrane transporter intereses intelectuales y afinidades personales que recuperaba, aunque con mucha más mod

• Previous studies have demonstrated localization of miR stain

  2019-05-30

  

  Previous studies have demonstrated localization of miR-21 staining in stromal faah inhibitor of OSCC associated with the tongue and mouth floor—this might be a useful prognostic predictor. We also observed miR-21 staining in the stromal cells of tumors. However, since multiple lines of evidence ind

• Clinical symptoms consist of the

  2019-05-30

  

  Clinical symptoms consist of the pacemaker syndrome, including palpitations and hemodynamic instability, as in our case. The definitive management of RNRVAS requires sufficient time for the atrial tissue to recover from the refractory period. Barold et al. reviewed several general modes that could p

• order AMG 925 br Conclusion br Conflict of interest br Intro

  2019-05-30

  

  Conclusion Conflict of interest Introduction Recent trials of the use of implantable electronic devices, including implantable cardioverter defibrillators (ICDs) and cardiac resynchronization therapy defibrillators (CRT-Ds) show survival benefits [1–3]. As a result, implantable electronic d

• Hereditary syndromes with increased risk for

  2019-05-30

  

  Hereditary syndromes with increased risk for gastric cancer include: 1) hereditary diffuse gastric cancer, 2) Lynch syndrome/hereditary non-polyposis colorectal cancer, 3) juvenile polyposis syndrome, 4) Peutz-Jeghers syndrome and 5) familial adenomatous polyposis. Hereditary diffuse gastric cancer

• br Introduction Patients with advanced breast prostate lung

  2019-05-30

  

  Introduction Patients with advanced breast, prostate, lung and colo-rectal cancer frequently develop bone metastases (BMs). These lesions may be asymptomatic or may cause pain, pathologic fractures, malignant hypercalcemia, epidural spinal cord compression and/or shorten survival [1]. The underly

• br Ethics br Funding br Conflicts of interest br Acknowledgm

  2019-05-30

  

  Ethics Funding Conflicts of interest Acknowledgments Case A 68-year-old man with palpitations was referred to our center for catheter ablation because of drug-refractory atrial fibrillation (AF). The preoperative multidetector computed tomography showed a congenital vascular anomaly:

• More than million almost children younger than

  2019-05-30

  

  More than 200 million—almost 40%—children younger than 5 years in developing countries are not fulfilling their developmental potential. In parts of Africa, up to three-quarters of children are victims of physical abuse, and a third of girls and more than 10% of boys are victims of sexual abuse. One

• All cases of obstetric fistula can be prevented

  2019-05-30

  

  All cases of obstetric fistula can be prevented with timely access to emergency obstetric care, especially caesarean section. Obstetric fistula was virtually eliminated in Europe and the USA between 1935 and 1950, because of universal access to safe delivery care. That it is still a public health pr

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